Publications

2026

Taguchi A*, Fujita J, Tanabe M, Takaya D, Harada K, Moriya T, Fukuzawa K, Namba K & Nishino K* (2026). Structural insights into fosfomycin efflux by a streptococcal ABC transporter. bioRxiv. https://doi.org/10.64898/2026.07.07.736899 (*co-corresponding authors)

2024

Taguchi A*, Nakashima R & Nishino K* (2024). Structural basis of nucleotide selectivity in pyruvate kinase. J. Mol. Biol. 104892 (*co-corresponding authors)

2023

Taguchi A*, Nakashima R & Nishino K* (2023). Functional characterization of Streptococcus pneumoniae pyruvate kinase involved in fosfomycin resistance. J. Biol. Chem. 104892 (*co-corresponding authors)

Park Y+, Taguchi A+, Baidin V, Kahne D & Walker S (2023). A time-resolved FRET assay identifies a small molecule that inhibits the essential bacterial cell wall polymerase FtsW. Angew. Chem. Int. Ed. e202301522 (+co-first authors)

Weaver A, Taguchi A & Dorr T (2023). Masters of misdirection: peptidoglycan glycosidases in bacterial growth. J. Bacteriol. 205, e00428-22

Hummels KR, Berry S, Li Z, Taguchi A, Min J, Walker S, Marks DS & Bernhardt TG (2023). Coordination of bacterial cell wall and outer membrane biogenesis. Nature. 615, 300-304

2021

Taguchi A, Page JE, Tsui HCT, Winkler ME & Walker S (2021). Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall. Proc. Natl. Acad. Sci. U.S.A. 118, e2103740118.

Perez AJ, Boersma MJ, Bruce KE, Lamanna MM, Shaw SL, Tsui HCT, Taguchi A, Carlson EE, VanNieuwenhze MS & Winkler ME (2021). Organization of peptidoglycan synthesis in nodes and separate rings at different stages of cell division of Streptococcus pneumoniae. Mol. Microbiol. 115, 1152-1169

2020

Sjodt M, Rohs PDA, Gilman MSA, Erlandson SC, Zheng S, Green AG, Brock KP, Taguchi A, Kahne D, Walker S, Marks DS, Rudner DZ, Bernhardt TG & Kruse AC (2020). Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nat. Microbiol. 5, 813–820

2019

Taguchi A, Kahne D & Walker S (2019). Chemical tools to characterize peptidoglycan synthases. Curr. Opin. Chem. Biol. 53, 44–50

Welsh MA, Schaefer K, Taguchi A, Kahne D & Walker S (2019). Direction of chain growth and substrate preferences of shape, elongation, division, and sporulation-family peptidoglycan glycosyltransferases. J. Am. Chem. Soc. 141, 12994–12997

Taguchi A, Welsh MA, Marmont LS, Lee W, Sjodt M, Kruse AC, Kahne D, Bernhardt TG & Walker S (2019). FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein. Nat. Microbiol. 4, 587–594

2017

Welsh MA, Taguchi A, Schaefer K, Van Tyne D, Lebreton F, Gilmore MS, Kahne D & Walker S (2017). Identification of a functionally unique family of penicillin-binding proteins. J. Am. Chem. Soc. 139, 17727-17730